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Glucomannan is used to manage constipation, diabetes, obesity, hypercholesterolemia, and hyperlipidemia. It’s also used to induce weight loss.

March 22, 2008 | Leave a Comment

Glucomannan is a dietary fiber, and has been marketed as a treatment for constipation, obesity, high cholesterol, Acne vulgaris (source) and Type 2 diabetes.I found great info about Glucomannan, which is the main ingredient in FibraSlim:

Glucomannan – Uses and Side Effects

Glucomannan is used to manage constipation, diabetes, obesity, hypercholesterolemia, and hyperlipidemia. It’s also used to induce weight loss. 

Mike Hussey
March 19, 2008
Glucomannan is a water-soluble polysaccharide composing 40% by dry weight of the roots or corm of the konjac plant. Glucomannan is a dietary fiber, and has been marketed as a treatment for constipation, obesity, high cholesterol, Acne vulgaris (source) and Type 2 diabetes. Glucomannan is also a hemicellulose that is present in large amounts in the wood of conifers and in smaller amounts in the wood of dicotyledons.

Reported uses

Glucomannan is used to manage constipation, diabetes, obesity, hypercholesterolemia, and hyperlipidemia. It’s also used to induce weight loss.

Administration

For diabetes: 3.6 to 7.2 g by mouth every day

For hyperlipidemia: 3.9 g by mouth every day

For weight loss: 1 g by mouth three times a day, 2 hours before each meal.

Hazards

Adverse reactions associated with glucomannan include esophageal obstruction, flatulence, diarrhea, and hypoglycemia. Glucomannan may cause significant hypoglycemia when given with oral antidiabetics or insulin. The fiber content of glucomannan may interfere with the absorption of various drugs.

Patients with a history of an allergic reaction to glucomannan or any of its components should avoid use. Patients with GI dysfunction, patients prone to hypoglycemia, and patients with underlying diabetes should use with caution.

Clinical considerations

Consuming glucomannan may result in a feeling of fullness, thereby decreasing the appetite.

Monitor patient for adverse effects such as esophageal obstruction, lower GI obstruction, flatulence, diarrhea, and hypoglycemia.

Monitor patient’s weight and serum cholesterol and serum glucose levels.

Advise patient to avoid using tablet form because it poses an increased risk of esophageal obstruction.

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